久保田 浩司 論文リスト

  

List of publication

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[31] TBA, Borylation
Hayama, K.; Kojima, R.; Kubota, K.; Ito, H.*

[30] TBA, Borylation
Akiyama, S.; Nomura, S.; Kubota, K.; Ito, H.*

[29] TBA, Mechanochemistry
Takahashi, R.; Kubota, K.*; Ito, H.* submitted.

[28] TBA, Mechanochemistry
Kubota, K.*; Pang, Y.; Miura, A.; Ito, H.* under revision.

[27] Solid-State Suzuki-Miyaura Cross-Coupling Reactions: Olefin-Accelerated C–C Coupling Using Mechanochemistry
Seo, T.; Ishiyama, T.; Kubota, K.*; Ito, H.* Chem. Sci. 2019, 10, 8202 - 8210.
DOI: 10.1039/C9SC02185J

[26] Catalytic Enantioselective Synthesis of Allylic Boronates Bearing a Trisubstituted Alkenyl Fluoride and Related Derivatives
Akiyama, S.; Kubota, K.; Mikus, M. S.; Paioti, P. H. S.; Romiti, F.; Liu, Q.; Zhou, Y.; Hoveyda, A. H.*; Ito, H.* Angew. Chem. Int. Ed. 2019, 58, 11998 - 12003.
DOI: 10.1002/anie.201906283

  

Highlighted as a Frontispiece in Issue 35, 2019

[25] Copper(I)-Catalyzed Enantioconvergent Borylation of Racemic Benzyl Chlorides Enabled by Quadrant-by-Quadrant Structure Modulation of Chiral Bisphosphine Ligands
Iwamoto, H.; Endo, K.; Ozawa, Y.; Watanabe, Y.; Kubota, K.; Imamoto, T.; Ito, H.* Angew. Chem. Int. Ed. 2019, 58, 11112 - 11117.
DOI: 10.1002/anie.201906011

[24] Synthesis of 2-alkyl-2-boryl-substituted-tetrahydrofurans via copper(I)-catalysed borylative cyclization of aliphatic ketones
Kubota, K.; Uesugi, M.; Osaki, S.; Ito, H.* Org. Biomol. Chem. 2019, 17, 5680 - 5683.
DOI: 10.1039/C9OB00962K

[23] Mechanochemistry allows carrying out sensitive organometallic reactions in air: Glove-box-and-Schlenk-line-free synthesis of oxidative addition complexes from aryl halides and palladium(0)
Kubota, K.*; Takahashi, R.; Ito, H.* Chem. Sci. 2019, 10, 5837 - 5842.
DOI: 10.1039/C9SC01711A

[22] Iridium(I)-Catalyzed C-H Borylation in Air by Using Mechanochemistry
Pang, Y.; Ishiyama, T.; Kubota, K.*; Ito, H.* Chem. Eur. J. 2019, 25, 4654 - 4659.
DOI: 10.1002/chem.201900685

[21] Olefin-accelerated solid-state C–N cross-coupling reactions using mechanochemistry
Kubota, K.*; Seo, T.; Koide, K.; Hasegawa, Y.; Ito, H.* Nature Communications 2019, 10, 111.
DOI: 10.1038/s41467-018-08017-9

https://www.nature.com/articles/s41467-018-08017-9

・北海道大学 PRESS RELEASE 固体状態で進行するクロスカップリング反応を開発
Behind the Paper (Nature Research Chemistry Community) Cross-Coupling in Solid Using Mechanochemistry
Highlighted in News Paper: 日経産業新聞20190111
Highlighted in News Paper: 日刊工業新聞20190115 
Highlighted in News Web: NHK 北大 医薬品合成で新手法開発
Highlighted in News Web: 環境展望台 北大 固体状態で進行する有機合成反応プロセスを開発
Selected as "Nature Communications Editor's Highlights" 
Highlighted in Phys.org.: Boosting solid state chemical reactions

Highlighted in Converter News: Olefin Enables Efficient Solvent-Free Cross-Coupling Reactions
Highlighted in Technology Networks: Olefin Makes Chemistry Greener

Highlighted in Chem Station: スポットライトリサーチ ”メカノケミストリーを用いた固体クロスカップリング反応"

[20] Copper(I)-Catalyzed Stereoselective Defluoroborylation of Aliphatic Gem-Difluoroalkenes
Ito, H.*; Seo, T.; Kojima, R.; Kubota, K. Chem. Lett. 2018, 47, 1330 - 1332.
DOI: 10.1246/cl.180656

[19] Enantioselective Synthesis of N,S-Acetals by an Oxidative Pummerer Type Transformation Using Phase-Transfer Catalysis
Biswas, S.; Kubota, K.; Orlandi, M.; Turberg, M.; Miles, D. H.; Sigman, M. S.; Toste, F. D. Angew. Chem. Int. Ed. 2018, 57, 589 - 593.
DOI: 10.1002/anie.201711277

[18] Palladium Oxidative Addition Complexes for Peptide and Protein Crosslinking
Kubota, K.; Dai, P.; Pentelute B. L.; Buchwald S. L. J. Am. Chem. Soc. 2018, 140, 3128 - 3133.
DOI: 10.1021/jacs.8b00172

[17] Copper(I)-Catalyzed Diastereoselective Dearomative Carboborylation of Indoles
Hayama, K.; Kubota, K.; Iwamoto, H.; Ito, H.* Chem. Lett. 2017, 46, 1800 - 1802.
DOI: 10.1246/cl.170825

[16] Copper(I)-Catalyzed Regio- and Stereoselective Intramolecular Alkylboration of Propargyl Ethers and Amines
Iwamoto, H.; Ozawa, Y.; Kubota, K.; Ito, H.* J. Org. Chem. 2017, 82, 10563 - 10573.
DOI: 10.1021/acs.joc.7b02071

[15] Stereodivergent Hydrodefluorination of gem-Difluoroalkenes: Selective Synthesis of (Z)- and (E)-Monofluoroalkenes
Kojima, R.; Kubota, K.; Ito, H.* Chem. Commun. 2017, 53, 10688 - 10691.
DOI: 10.1039/C7CC05225A

・Highlighted in Synfacts 2018, 14, 55. DOI: 10.1055/s-0036-1591076

[14] Copper(I)-Catalyzed Enantioselective Nucleophilic Borylation of Ketones: Synthesis of Enantioenriched Chiral Tertiary alpha-Hydroxyboronates
Kubota, K.; Osaki, S.; Jin, M.; Ito, H.* Angew. Chem. Int. Ed. 2017, 56, 6646 - 6650.
DOI: 10.1002/anie.201702826

北海道大学 PRESS RELEASE 

・Highlighted in Synfacts 201713, 745. DOI: 10.1055/s-0036-1590558

[13] Synthesis of Enantiomerically Enriched Chiral Tetrahydroquinolines via Sequential Dearomatization/Enantioselective Borylation Reactions
Kubota, K.; Watanabe, Y.; Ito, H.* Adv. Synth. Catal. 2016, 358, 15, 2379 - 2384.
DOI: 10.1002/adsc.201600372


abstract_quinoline

[12] Computational Insight into the Enantioselective Nucleophilic Borylation of a Polarized C=O Double Bond Catalyzed by Di-phosphine-Borylcopper(I) Complexes
Kubota, K.; Jin, M.; Ito, H.* Organometallics 2016, 35, 1376 - 1383.
DOI: 10.1021/acs.organomet.5b00621

 

org

[11] Enantioselective Synthesis of Chiral Piperidines via the Stepwise Dearomatization/Borylation of Pyridines
Kubota, K.; Watanabe, Y.; Hayama, K.; Ito, H.* J. Am. Chem. Soc. 2016, 138, 13, 4338 - 4341.
DOI: 10.1021/jacs.6b01375

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[10] Highly Selective Markovnikov Hydroboration of Alkyl-Substituted Terminal Alkenes with a Phosphine-Copper(I) Catalyst
Iwamoto, H.; Kubota, K.; Ito, H. Chem. Commun. 2016, 5916 - 5919.
DOI: 10.1039/C6CC00782A

MHB_GA_1 (1)   iwamoto_cover
Highlighted as a Back Cover in Issue 35, 2016

[9] Copper(I)-Catalyzed Diastereoselective Borylative Exo-Cyclization of Alkenyl Aryl Ketones
Yamamoto, E.; Kojima, R.; Kubota, K.; Ito, H. Synlett 2015, 27, 2, 272 - 276.
DOI: 10.1055/s-0035-1560721

https://www.thieme-connect.de/media/synlett/EFirst/i_u0477_ga_10-1055_s-0035-1560721.gif

[8] Enantioselective Borylative Dearomatization of Indoles through Copper(I) Catalysis
Kubota, K.; Hayama, K.; Iwamoto, H.; Ito, H. Angew. Chem. Int. Ed. 2015, 54, 8809 - 8813.
DOI: 10.1002/anie.201502964

1511291_784871204944392_5626421871371438753_n

・Highlighted in Synfacts 2015, 11, 840. DOI: 10.1055/s-0034-1381153

[7] Copper(I)-Catalyzed Carbon–Halogen Bond-Selective Boryl Substitution of Alkyl Halides Bearing Terminal Alkene Moieties
Iwamoto, H.; Kubota, K.; Yamamoto, E; Ito, H. Chem. Comm. 2015, 51, 9655 - 9658.
DOI: 10.1039/C5CC02760H

名称未設定名称未設定

[6] Reaction Optimization, Scalability, and Mechanistic Insight on the Catalytic Enantioselective Desymmetrization of 1,1-Diborylalkanes via Suzuki–Miyaura Cross-Coupling
Sun, H.; Kubota, K.; Hall, D. G. Chem. Eur. J. 2015, Early View
DOI: doi/10.1002/chem.201406680

mcontent

[5] Silicon-Tethered Strategy for Copper(I)-Catalyzed Stereo- and Regioselective Alkylboration of Alkynes
Kubota, K.; Iwamoto, H.; Yamamoto, E; Ito, H. Org. Lett. 2015, 17, 620 - 623.
DOI: 10.1021/ol503620n

ol-2014-03620n_0007 

・Highlighted in Synfacts 2015, 11, 406. DOI: 10.1055/s-0034-1380388

 

[4] Copper(I)-Catalyzed Enantioselective Nucleophilic Borylation of Aldehydes: An Efficient Route to Enantiomerically Enriched α-Alkoxyorganoboronate Esters
Kubota, K.; Yamamoto, E.; Ito, H. J. Am. Chem. Soc. 2015, 137, 1, 420 - 424.
DOI: 10.1021/ja511247z

kubotaabs 

・Highlighted in Synfacts 2015, 11, 286. DOI: 10.1055/s-0034-1380053

[3] Regio- and Enantioselective Monoborylation of Alkenylsilanes Catalyzed by an Electron-Donating Chiral Phosphine-opper(I) Complex
Kubota, K.; Yamamoto, E.; Ito, H. Advanced Synthesis & Catalysis 2013, 355, 3527 - 3531.
DOI: 10.1002/adsc.201300765

mcontent

・Highlighted in Synfacts, 2013, 10, 284. DOI: 10.1055/s-0033-1340694

[2] Copper(I)-Catalyzed Borylative Exo-Cyclization of Alkenyl Halides Containing Unactivated Double Bond
Kubota, K.; Yamamoto, E.; Ito, H. J. Am. Chem. Soc. 2013, 135, 2635 - 2640.
DOI: 10.1021/ja3104582

HP1_450

[1] Copper(I)-Catalyzed Boryl Substitution of Unactivated Alkyl Halides
Ito, H.; Kubota, K. Org. Lett. 2012, 14, 890 - 893.
DOI: 10.1021/ol203413w

Abstract Image

Reviews

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[3] Formal Nucleophilic Borylation and Borylative Cyclization of Organic Halides
Kubota, K.; Iwamoto, H.; Ito, H.* Org. Biomol. Chem. 2017, 15, 285 - 300.
DOI: 10.1039/C6OB02369J

OBC review

• Selected as the most cited and accessed articles published in Organic & Biomolecular Chemistry (OBC) in 2017.

[2] Topochemical Photocyclizations for the Synthesis of Two-Dimensional Polymers
Kubota, K. J. Synth. Org. Chem. Jpn. 2014, 72, 834.
DOI: 10.5059/yukigoseikyokaishi.72.834

[1] Selective Synthesis of Organoboron Compounds with Copper(I)-Phosphine Complex Catalysts
Yamamoto, E.; Takenouchi, Y.; Kubota, K.; Ito, H. J. Synth. Org. Chem. Jpn. 2014, 72, 758 - 769.
DOI: 10.5059/yukigoseikyokaishi.72.758